Anti-NUAK2 抗体 - Aminoterminal end (ab71398)

製品の概要

  • 製品名
    Anti-NUAK2 antibody - Aminoterminal end
    NUAK2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NUAK2 - Aminoterminal end
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the N-terminal region of human NUAK2.

  • ポジティブ・コントロール
    • Transfected/ non-transfected 293 cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab71398 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Detects a band of approximately 80 kDa (predicted molecular weight: 70 kDa).
ELISA 1/1000.

ターゲット情報

  • 機能
    Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
  • 配列類似性
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
    Contains 1 protein kinase domain.
  • 翻訳後修飾
    Phosphorylated at Thr-208 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Autophosphorylated in vitro.
  • Information by UniProt
  • 参照データベース
  • 製品の状態
    Involved in actin cytoskeleton organization.
  • 別名
    • DKFZp434J037 antibody
    • DKFZp686F01113 antibody
    • FLJ90349 antibody
    • NUAK family SNF1 like kinase 2 antibody
    • NUAK family SNF1-like kinase 2 antibody
    • Nuak2 antibody
    • NUAK2_HUMAN antibody
    • Omphalocele kinase 2 antibody
    • SNARK antibody
    • SNF1/AMP activated protein kinase antibody
    • SNF1/AMP kinase related kinase antibody
    • SNF1/AMP kinase-related kinase antibody
    see all

画像

  • All lanes : Anti-NUAK2 antibody - Aminoterminal end (ab71398) at 1/50 dilution

    Lane 1 : Non-transfected 293 cell line lysates
    Lane 2 : NUAK2 transfected 293 cell line lysates

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 70 kDa
    Observed band size : 80 kDa (why is the actual band size different from the predicted?)

プロトコール

参考文献

ab71398 has not yet been referenced specifically in any publications.

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