製品の概要

  • 製品名Anti-NSE2 antibody
    NSE2 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to NSE2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    NSE2 (NP_775956) full length human protein.

  • ポジティブ・コントロール
    • NSE2 transfected lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab71976 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 28 kDa.

ターゲット情報

  • 機能E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.
  • パスウェイProtein modification; protein sumoylation.
  • 配列類似性Belongs to the NSE2 family.
    Contains 1 SP-RING-type zinc finger.
  • 翻訳後修飾Sumoylated, possibly via autosumoylation.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C8orf36 antibody
    • E3 SUMO-protein ligase NSE2 antibody
    • hMMS21 antibody
    • hNSE2 antibody
    • methyl methanesulfonate sensitivity gene 21 antibody
    • MMS21 antibody
    • MMS21 homolog antibody
    • non-SMC element 2 antibody
    • Non-SMC element 2 homolog antibody
    • Non-structural maintenance of chromosomes element 2 homolog antibody
    • NSE2_HUMAN antibody
    • Nsmce2 antibody
    see all

Anti-NSE2 antibody 画像

  • All lanes : Anti-NSE2 antibody (ab71976) at 1/500 dilution

    Lane 1 : NSE2 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

    Predicted band size : 28 kDa
    Observed band size : 32 kDa (why is the actual band size different from the predicted?)

Anti-NSE2 antibody (ab71976) 使用論文

ab71976 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab71976.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"