製品の概要

  • 製品名
    Anti-Nrf2 antibody, prediluted
    Nrf2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Nrf2, prediluted
  • 特異性
    ab31164 recognises Nrf2 protein.
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Chicken, Cow, Dog
  • 免疫原

    Synthetic peptide:

    TL YLEVFSMLRD EDGKPYSPS

    , corresponding to amino acids 569-588 of Human Nrf2

  • ポジティブ・コントロール
    • Placenta

アプリケーション

Our Abpromise guarantee covers the use of ab31164 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: use neat for 30 min at RT. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol, by boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
    • 組織特異性
      Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.
    • 配列類似性
      Belongs to the bZIP family. CNC subfamily.
      Contains 1 bZIP domain.
    • ドメイン
      Acidic activation domain in the N-terminus, and DNA binding domain in the C-terminus.
    • 翻訳後修飾
      Phosphorylation of Ser-40 by PKC in response to oxidative stress dissociates NFE2L2 from its cytoplasmic inhibitor KEAP1, promoting its translocation into the nucleus.
    • 細胞内局在
      Cytoplasm > cytosol. Nucleus. Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.
    • Information by UniProt
    • 参照データベース
    • 別名
      • erythroid derived 2 antibody
      • HEBP1 antibody
      • like 2 antibody
      • NF E2 related factor 2 antibody
      • NF-E2-related factor 2 antibody
      • NF2L2_HUMAN antibody
      • NFE2 related factor 2 antibody
      • NFE2-related factor 2 antibody
      • Nfe2l2 antibody
      • Nrf 2 antibody
      • NRF2 antibody
      • Nuclear factor (erythroid derived 2) like 2 antibody
      • Nuclear factor antibody
      • nuclear factor erythroid 2 like 2 antibody
      • Nuclear factor erythroid 2 related factor 2 antibody
      • Nuclear factor erythroid 2-related factor 2 antibody
      • Nuclear factor erythroid derived 2 like 2 antibody
      see all

    Anti-Nrf2 antibody, prediluted 画像

    • Human placenta stained with anti-Nrf2 (ab31164, pre-diluted)

    プロトコール

    Anti-Nrf2 antibody, prediluted (ab31164) 使用論文

    ab31164 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab31164.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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