製品の概要

  • 製品名
    Anti-NPTN antibody
    NPTN 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NPTN
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide from the N terminal domain of Human NPTN (NP_036560.1).

  • ポジティブ･コントロール
    • Human breast and colon tissues

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファー
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab118883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 15 - 20 µg/ml.

ターゲット情報

  • 機能
    Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity.
  • 組織特異性
    Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level).
  • 配列類似性
    Contains 3 Ig-like (immunoglobulin-like) domains.
  • ドメイン
    Some isoforms lack the first Ig-like domain which may confer homophilic adhesion activity. However, they can bind and activate FGFR1.
  • 翻訳後修飾
    N-glycosylated.
  • 細胞内局在
    Cell membrane. Enriched at post-synaptic density.
  • Information by UniProt
  • 参照データベース
    • 別名
      • GP55 antibody
      • GP65 antibody
      • Neuroplastin antibody
      • np55 antibody
      • np65 antibody
      • Nptn antibody
      • NPTN_HUMAN antibody
      • SDFR1 antibody
      • SDR-1 antibody
      • SDR1 antibody
      • stromal cell derived factor receptor 1 antibody
      • Stromal cell-derived receptor 1 antibody
      see all

    画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NPTN antibody (ab118883)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NPTN antibody (ab118883)
      Formalin fixed, paraffin embedded Human breast tissue stained with ab11883 at 20 µg/ml.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NPTN antibody (ab118883)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NPTN antibody (ab118883)
      Formalin fixed, paraffin embedded Human colon tissue stained with ab11883 at 20 µg/ml.

    プロトコール

    参考文献

    ab118883 has not yet been referenced specifically in any publications.

    ab118883 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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