Anti-NPTN 抗体 (ab118883)

製品の概要

• 製品名Anti-NPTN antibody
  NPTN 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to NPTN
• アプリケーション適用あり: IHC-Pmore details
• 種交差性
  交差種: Human
  
• 免疫原

  KLH conjugated synthetic peptide from the N terminal domain of Human NPTN (NP_036560.1).

• ポジティブ･コントロール
  • Human breast and colon tissues

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
• バッファーPreservative: 0.1% Sodium azide
  Constituent: 99% PBS
• Concentration information loading...
• 精製度Immunogen affinity purified
• ポリ/モノポリクローナル
• アイソタイプIgG
• 研究分野
  • Cancer
  • Tumor immunology
  • Tumor-associated antigens

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • Colon (human) normal tissue slides (ab4327)

アプリケーション

ターゲット情報

• 機能Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity.
• 組織特異性Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level).
• 配列類似性Contains 3 Ig-like (immunoglobulin-like) domains.
• ドメインSome isoforms lack the first Ig-like domain which may confer homophilic adhesion activity. However, they can bind and activate FGFR1.
• 翻訳後修飾N-glycosylated.
• 細胞内局在Cell membrane. Enriched at post-synaptic density.

• Target information above from: UniProt accession Q9Y639 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 27020 Human
  • Omim: 612820 Human
  • SwissProt: Q9Y639 Human
  • Unigene: 713221 Human
• 別名
  • GP55 antibody
  • GP65 antibody
  • Neuroplastin antibody

  • np55 antibody
  • np65 antibody
  • Nptn antibody
  • NPTN_HUMAN antibody
  • SDFR1 antibody
  • SDR-1 antibody
  • SDR1 antibody
  • stromal cell derived factor receptor 1 antibody
  • Stromal cell-derived receptor 1 antibody

  see all