製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to NPR2L
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Cow, Xenopus laevis, Zebrafish
  • 免疫原

    Synthetic peptide:

    QYSNVYCPTPKV

    , corresponding to amino acids 240-251 of Human NPR2L (NP_006536.3).

  • ポジティブ・コントロール
    • Human skeletal muscle lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77349 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報
    Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/32000.
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 44 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.
    • 組織特異性
      Most abundant in skeletal muscle, followed by brain, liver and pancreas, with lower amounts in lung, kidney, placenta and heart. Expressed in most lung cancer cell lines tested.
    • 配列類似性
      Belongs to the NPR2 family.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 2810446G01Rik antibody
      • G21 protein antibody
      • Gene 21 protein antibody
      • Homologous to yeast nitrogen permease (candidate tumor suppressor) antibody
      • Homologous to yeast nitrogen permease antibody
      • Nitrogen permease regulator 2-like protein antibody
      • Nitrogen permease regulator-like 2 (S. cerevisiae) antibody
      • NPR 2L antibody
      • NPR L2 antibody
      • NPR like 2 antibody
      • NPR2 antibody
      • NPR2 like antibody
      • NPR2-like protein antibody
      • NPR2L antibody
      • NPRL 2 antibody
      • NPRL2 antibody
      • NPRL2_HUMAN antibody
      • Tumor suppressor candidate 4 antibody
      • TUSC 4 antibody
      • TUSC 4 protein antibody
      • TUSC4 antibody
      • TUSC4 protein antibody
      see all

    Anti-NPR2L antibody 画像

    プロトコール

    Anti-NPR2L antibody (ab77349) 使用論文

    ab77349 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab77349.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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