製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to NPR2L
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Cow, Xenopus laevis, Zebrafish
  • 免疫原

    Synthetic peptide:

    QYSNVYCPTPKV

    , corresponding to amino acids 240-251 of Human NPR2L (NP_006536.3).

  • ポジティブ・コントロール
    • Human skeletal muscle lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77349 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報
    Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/32000.
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 44 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.
    • 組織特異性
      Most abundant in skeletal muscle, followed by brain, liver and pancreas, with lower amounts in lung, kidney, placenta and heart. Expressed in most lung cancer cell lines tested.
    • 配列類似性
      Belongs to the NPR2 family.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 2810446G01Rik antibody
      • G21 protein antibody
      • Gene 21 protein antibody
      • Homologous to yeast nitrogen permease (candidate tumor suppressor) antibody
      • Homologous to yeast nitrogen permease antibody
      • Nitrogen permease regulator 2-like protein antibody
      • Nitrogen permease regulator-like 2 (S. cerevisiae) antibody
      • NPR 2L antibody
      • NPR L2 antibody
      • NPR like 2 antibody
      • NPR2 antibody
      • NPR2 like antibody
      • NPR2-like protein antibody
      • NPR2L antibody
      • NPRL 2 antibody
      • NPRL2 antibody
      • NPRL2_HUMAN antibody
      • Tumor suppressor candidate 4 antibody
      • TUSC 4 antibody
      • TUSC 4 protein antibody
      • TUSC4 antibody
      • TUSC4 protein antibody
      see all

    画像

    プロトコール

    参考文献

    ab77349 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab77349.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    登録