製品の概要

  • 製品名
    Anti-NPEPPS antibody [2649C4a]
    NPEPPS 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2649C4a] to NPEPPS
  • アプリケーション
    適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment comprising of 50-200 amino acids from the internal region of human NPEPPS.

  • ポジティブ・コントロール
    • Recombinant fragment of human NPEPPS.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, (8.0mM Sodium phosphate, 3.0mM Potassium chloride, 140mM Sodium chloride, 1.5mM Potassium phosphate), pH 7.4
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    ab76558 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
  • ポリ/モノ
    モノクローナル
  • クローン名
    2649C4a
  • アイソタイプ
    IgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab76558 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.2 - 2 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 103 kDa).
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain.
  • 組織特異性
    Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level).
  • 配列類似性
    Belongs to the peptidase M1 family.
  • 細胞内局在
    Cytoplasm > cytosol. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AAP-S antibody
    • Aminopeptidase puromycin sensitive antibody
    • Cytosol alanyl aminopeptidase antibody
    • Metalloprotease 100 antibody
    • Metalloprotease MP100 antibody
    • MP 100 antibody
    • MP100 antibody
    • Npepps antibody
    • Psa antibody
    • PSA_HUMAN antibody
    • Puromycin sensitive aminopeptidase antibody
    • Puromycin-sensitive aminopeptidase antibody
    see all

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プロトコール

参考文献

ab76558 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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