製品の概要

  • 製品名
    Anti-NOSTRIN antibody
  • 製品の詳細
    Rabbit polyclonal to NOSTRIN
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 217-247 of Human NOSTRIN (NP_443178.2, NP_001034813.2, NP_001165103.1, NP_001165102.1).

  • ポジティブ・コントロール
    • HepG2 cell line and Mouse heart tissue lysates.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab116374 is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab116374 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 58 kDa.

ターゲット情報

  • 機能
    Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
  • 組織特異性
    Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen. Present in vascular endothelial cells and placenta. Over-expressed in placenta from women with pre-eclampsia (at protein level).
  • 配列類似性
    Contains 1 FCH domain.
    Contains 1 SH3 domain.
  • ドメイン
    The SH3 domain mediates interaction with NOS3, DNM2 and WASL.
    The FCH domain is necessary for membrane targeting.
  • 細胞内局在
    Cell membrane. Cytoplasmic vesicle. Cytoplasm > cytoskeleton. Enriched in selected actin structures.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BM247 antibody
    • BM247 homolog antibody
    • DaIP2 antibody
    • eNOS-trafficking inducer antibody
    • mDaIP2 antibody
    • MGC20702 antibody
    • Nitric oxide synthase traffic inducer antibody
    • Nitric oxide synthase trafficker antibody
    • NOSTN_HUMAN antibody
    • Nostrin antibody
    • RP23-431D4.2 antibody
    see all

画像

  • Anti-NOSTRIN antibody (ab116374) at 1/100 dilution + HepG2 cell line lysate at 35 µg

    Predicted band size : 58 kDa
  • Anti-NOSTRIN antibody (ab116374) at 1/100 dilution + Mouse heart tissue lysate at 35 µg

    Predicted band size : 58 kDa

プロトコール

参考文献

ab116374 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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