Anti-Non Neuronal Enolase 抗体 [8G8] (ab118866)

製品の概要

  • 製品名Anti-Non Neuronal Enolase antibody [8G8]
    Non Neuronal Enolase 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [8G8] to Non Neuronal Enolase
  • アプリケーション適用あり: WB, ELISA, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-435 of Human Non Neuronal Enolase with a proprietary tag.

  • ポジティブ・コントロール
    • Human breast tissue, Human pancreas tissue, Human heart tissue, HeLa cells, MCF-7 (Human breast adenocarcinoma cell line) lysate and 293T cell transfected lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab118866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 47 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
    MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.
  • 組織特異性The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
  • パスウェイCarbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
  • 配列類似性Belongs to the enolase family.
  • 発生段階During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.
  • 翻訳後修飾ISGylated.
  • 細胞内局在Nucleus and Cytoplasm. Cell membrane. Cytoplasm > myofibril > sarcomere > M line. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M line.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2-phospho-D-glycerate hydro-lyase antibody
    • alpha enolase like 1 antibody
    • Alpha-enolase antibody
    • bh3 interacting domain death agonist antibody
    • c-myc promoter-binding protein 1 antibody
    • C-myc promoter-binding protein antibody
    • c-myc promoter-binding protein-1 antibody
    • eno1 antibody
    • ENO1L1 antibody
    • ENOA_HUMAN antibody
    • enolase 1 (alpha) antibody
    • Enolase 1 antibody
    • HAP 47 antibody
    • HAP47 antibody
    • MBP-1 antibody
    • MPB 1 antibody
    • MPB-1 antibody
    • MPB1 antibody
    • MYC promoter-binding protein 1 antibody
    • NNE antibody
    • Non-neural enolase antibody
    • OTTHUMP00000001706 antibody
    • Phosphopyruvate hydratase antibody
    • Plasminogen-binding protein antibody
    • PPH antibody
    • tau-crystallin antibody
    see all

Anti-Non Neuronal Enolase antibody [8G8] 画像

  • ab118866 at 5 µg/ml staining Non Neuronal Enolase in Paraffin-embedded Human breast tissue by immunohistochemistry.
  • ab118866 at 5 µg/ml staining Non Neuronal Enolase in Paraffin-embedded Human heart tissue by immunohistochemistry.
  • ab118866 at 5 µg/ml staining Non Neuronal Enolase in Paraffin-embedded Human pancreas tissue by immunohistochemistry.
  • ab118866 at 10 µg/ml staining Non Neuronal Enolase in Paraffin-embedded HeLa tissue by immunofluorescence.
  • All lanes : Anti-Non Neuronal Enolase antibody [8G8] (ab118866)

    Lane 1 : Transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate


    Predicted band size : 47 kDa
  • Anti-Non Neuronal Enolase antibody [8G8] (ab118866) + MCF-7 lysate

    Predicted band size : 47 kDa

Anti-Non Neuronal Enolase antibody [8G8] (ab118866) 使用論文

ab118866 has not yet been referenced specifically in any publications.

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