製品の概要

  • 製品名Anti-Nodal antibody [EP2058Y]
    Nodal 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EP2058Y] to Nodal
  • 特異性ab81287 detects Pro-Nodal and Nodal.
  • アプリケーション適用あり: Flow Cyt, WBmore details
    適用なし: IHC-P or IP
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to residues near the C-terminus of human Nodal.

  • ポジティブ・コントロール
    • Recombinant nodal protein.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名EP2058Y
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab81287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt 1/60.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

WB 1/2000. Predicted molecular weight: 39 kDa. (Pro-Nodal) and 13 kDa (Nodal).
  • 追加情報Is unsuitable for IHC-P or IP.
  • ターゲット情報

    • 機能Essential for mesoderm formation and axial patterning during embryonic development.
    • 関連疾患Defects in NODAL are the cause of visceral heterotaxy autosomal type 5 (HTX5) [MIM:270100]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy autosomal type 5 include situs inversus viscerum or situs ambiguus, congenital heart defect, transposition of the great vessels ventricular septal defect, atrial septal defect, truncuscommunis, and dextrocardia.
    • 配列類似性Belongs to the TGF-beta family.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • HTX5 antibody
      • MGC138230 antibody
      • Nodal antibody
      • Nodal Growth Differentiation Factor antibody
      • nodal homolog (mouse) antibody
      • Nodal homolog antibody
      • Nodal, Mouse, Homolog antibody
      • NODAL_HUMAN antibody
      see all

    Anti-Nodal antibody [EP2058Y] 画像

    • Anti-Nodal antibody [EP2058Y] (ab81287) at 1/2000 dilution + Recombinant nodal protein at 10ng

      Secondary
      HRP conjugated goat anti-rabbit at 1/2000 dilution

      Predicted band size : 39 kDa
      Observed band size : 15 kDa (why is the actual band size different from the predicted?)

    Anti-Nodal antibody [EP2058Y] (ab81287) 使用論文

    This product has been referenced in:

    See 1 Publication for this product

    Product Wall

    Thank you for contacting Abcam.

    The immunogen for ab81287 is downstream of Nodal residue XXX.

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Free Ra...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"