Anti-NMNAT3 抗体 (ab121030)
Key features and details
- Goat polyclonal to NMNAT3
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-NMNAT3 antibody
NMNAT3 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to NMNAT3 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Rat -
免疫原
Synthetic peptide:
C-KALGQGQSVKYLLPE
, corresponding to internal sequence amino acids 206-220 of Mouse NMNAT3 (NP_653116.1). -
ポジティブ・コントロール
- Mouse heart lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation, followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab121030の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).
1 hour primary incubation is recommended for this product. |
特記事項 |
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WB
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa). 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury. -
組織特異性
Expressed in lung and spleen with lower levels in placenta and kidney. -
パスウェイ
Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1. -
配列類似性
Belongs to the eukaryotic NMN adenylyltransferase family. -
細胞内局在
Mitochondrion. - Information by UniProt
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参照データベース
- Entrez Gene: 74080 Mouse
- Entrez Gene: 363118 Rat
- SwissProt: Q99JR6 Mouse
- Unigene: 294082 Mouse
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別名
- NaMN adenylyltransferase 3 antibody
- Nicotinamide mononucleotide adenylyltransferase 3 antibody
- Nicotinamide nucleotide adenylyltransferase 3 antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (3)
ab121030 は 3 報の論文で使用されています。
- Yoshida N et al. Relationship between Cognitive Dysfunction and Age-Related Variability in Oxidative Markers in Isolated Mitochondria of Alzheimer's Disease Transgenic Mouse Brains. Biomedicines 10:N/A (2022). PubMed: 35203488
- Crisol BM et al. NAD+ precursor increases aerobic performance in mice. Eur J Nutr 59:2427-2437 (2020). PubMed: 31494696
- Wang X et al. Subcellular NAMPT-mediated NAD+ salvage pathways and their roles in bioenergetics and neuronal protection after ischemic injury. J Neurochem 151:732-748 (2019). PubMed: 31553812