製品の概要

  • 製品名Anti-NMNAT3 antibody
    NMNAT3 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to NMNAT3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide:

    C-KALGQGQSVKYLLPE

    , corresponding to internal sequence amino acids 206-220 of Mouse NMNAT3 (NP_653116.1).

  • ポジティブ・コントロール
    • Mouse heart lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab121030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).Can be blocked with ab185635.

ターゲット情報

  • 機能Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury.
  • 組織特異性Expressed in lung and spleen with lower levels in placenta and kidney.
  • パスウェイCofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.
  • 配列類似性Belongs to the eukaryotic NMN adenylyltransferase family.
  • 細胞内局在Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • NaMN adenylyltransferase 3 antibody
    • Nicotinamide mononucleotide adenylyltransferase 3 antibody
    • Nicotinamide nucleotide adenylyltransferase 3 antibody
    • Nicotinate-nucleotide adenylyltransferase 3 antibody
    • NMN adenylyltransferase 3 antibody
    • NMNA3_HUMAN antibody
    • NMNAT 3 antibody
    • Nmnat3 antibody
    • PNAT 3 antibody
    • PNAT-3 antibody
    • PNAT3 antibody
    • Pyridine nucleotide adenylyltransferase 3 antibody
    see all

Anti-NMNAT3 antibody 画像

  • Anti-NMNAT3 antibody (ab121030) at 0.5 µg/ml + Mouse heart lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 28 kDa
    Observed band size : 28 kDa
    Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

Anti-NMNAT3 antibody (ab121030) 使用論文

ab121030 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"