製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to NMDAR2B
  • アプリケーション
    適用あり: WB, IPmore details
  • 種交差性
    交差種: Mouse, Rat
    交差が予測される動物種: Human
  • 免疫原

    Amino acids 1437-1456 of mature mouse NR2B or 1463-1482 of NR2B precursor; signal is amino acid residues 1-26 [KFNGSSNGHV-YEKLSSIESDV].

  • ポジティブ・コントロール
    • Rat brain microsomal protein preparation.
  • 特記事項
    For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab14400 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
  • 追加情報
    IP: Use at a concentration of 5 µg.
    WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 180 kDa (predicted molecular weight: 178 kDa).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
    • 組織特異性
      Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.
    • 配列類似性
      Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily.
    • 細胞内局在
      Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AW490526 antibody
      • EIEE27 antibody
      • Glutamate [NMDA] receptor subunit epsilon 2 antibody
      • Glutamate [NMDA] receptor subunit epsilon-2 antibody
      • Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody
      • Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody
      • Glutamate receptor ionotropic NMDA2B antibody
      • Glutamate receptor subunit epsilon 2 antibody
      • Glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody
      • GRIN 2B antibody
      • GRIN2B antibody
      • hNR 3 antibody
      • hNR3 antibody
      • MGC142178 antibody
      • MGC142180 antibody
      • MRD6 antibody
      • N methyl D asparate receptor channel subunit epsilon 2 antibody
      • N methyl D aspartate receptor subtype 2B antibody
      • N methyl D aspartate receptor subunit 2B antibody
      • N methyl D aspartate receptor subunit 3 antibody
      • N-methyl D-aspartate receptor subtype 2B antibody
      • N-methyl-D-aspartate receptor subunit 3 antibody
      • NMDA NR2B antibody
      • NMDA R2B antibody
      • NMDAR2B antibody
      • NMDE2 antibody
      • NMDE2_HUMAN antibody
      • NME2 antibody
      • NR2B antibody
      • NR3 antibody
      see all

    参考文献

    This product has been referenced in:
    • Norcini M  et al. NR2B Expression in Rat DRG Is Differentially Regulated Following Peripheral Nerve Injuries That Lead to Transient or Sustained Stimuli-Evoked Hypersensitivity. Front Mol Neurosci 9:100 (2016). WB ; Rat . Read more (PubMed: 27803647) »
    • Rodríguez-Muñoz M  et al. The ON:OFF switch, s1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders. Oncotarget 6:35458-77 (2015). IP . Read more (PubMed: 26461475) »

    See all 6 Publications for this product

    レビューと Q&A

    Thank you for your patience.

    I have determined that the immunogen for Anti-NMDAR2B antibody ab14400 is not commercially available. The amino acid sequence is KFNGSSNGHVYEKLSSIESDV. We do not, however, offer a peptide synthesis service.
    ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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