製品の概要

  • 製品名Anti-NLRX1 antibody
    NLRX1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to NLRX1
  • 特異性ab106756 is expected to recognize both reported isoforms (NP_078894.2; NP_733840.1).
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide:

    C-NFSGETLDSTDPSN

    , corresponding to internal sequence amino acids 405-419 of Human NLRX1 (NP_078894.2; NP_733840.1).

  • ポジティブ・コントロール
    • Human Breast cancer lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab106756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 108 kDa).

ターゲット情報

  • 機能Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
  • 組織特異性Ubiquitously expressed. Strongest expression in mammary gland, heart and muscle. Detected in HELA, 293T, THP-1, HL60, RAJI, and JURKAT cell lines (at protein level).
  • 配列類似性Belongs to the NLRP family.
    Contains 7 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • 細胞内局在Mitochondrion outer membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Caterpiller protein 11.3 antibody
    • CLR11.3 antibody
    • DLNB26 antibody
    • FLJ21478 antibody
    • MGC131937 antibody
    • MGC21025 antibody
    • NLR family member X1 antibody
    • NLR family, X1 antibody
    • Nlrx1 antibody
    • NLRX1_HUMAN antibody
    • NOD-like receptor X1 antibody
    • NOD26 antibody
    • NOD5 antibody
    • NOD9 antibody
    • Nucleotide-binding oligomerization domain protein 26 antibody
    • Nucleotide-binding oligomerization domain protein 5 antibody
    • Nucleotide-binding oligomerization domain protein 9 antibody
    • nucleotide-binding oligomerization domain, leucine rich repeat containing X1 antibody
    • Protein Caterpiller 11.3 antibody
    see all

Anti-NLRX1 antibody 画像

  • Anti-NLRX1 antibody (ab106756) at 2 µg/ml + Human Breast cancer lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 108 kDa

Anti-NLRX1 antibody (ab106756) 使用論文

ab106756 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"