Anti-NLRP11 抗体 (ab105408)
Key features and details
- Rabbit polyclonal to NLRP11
- Suitable for: ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-NLRP11 antibody -
製品の詳細
Rabbit polyclonal to NLRP11 -
由来種
Rabbit -
特異性
At least three isoforms of NLRP11 are known to exist; this antibody will recognize all of them. NLRP11 antibody is predicted to not cross-react with other NLRP family members -
アプリケーション
適用あり: ICC/IF, WBmore details -
種交差性
交差種: Human -
免疫原
A 15 amino acid peptide from near the C terminus of Human NLRP11 (NP_659444).
-
ポジティブ・コントロール
- HeLa cell lysate
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab105408の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ICC/IF |
Use a concentration of 20 µg/ml.
|
|
WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 118 kDa.
|
特記事項 |
---|
ICC/IF
Use a concentration of 20 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 118 kDa. |
ターゲット情報
-
機能
Involved in inflammation. -
配列類似性
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 NACHT domain. - Information by UniProt
-
参照データベース
- Entrez Gene: 204801 Human
- Omim: 609664 Human
- SwissProt: P59045 Human
- Unigene: 375039 Human
-
別名
- CLR19.6 antibody
- FLJ26273 antibody
- NACHT leucine rich repeat and PYD containing 11 antibody
see all
画像
-
Immunofluorescence of NLRP11 in HeLa cells with ab105407 at 20 ug/mL.
-
Immunocytochemistry of HeLa cells with ab105408 at 2.5 μg/mL.
-
Anti-NLRP11 antibody (ab105408) at 1 µg/ml + HeLa cell lysate at 15 µg
Predicted band size: 118 kDa
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab105408 は 1 報の論文で使用されています。
- Gangopadhyay A et al. NLRP3 licenses NLRP11 for inflammasome activation in human macrophages. Nat Immunol 23:892-903 (2022). PubMed: 35624206