製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to NLRC5
  • アプリケーション
    適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH, from the N terminus of Human NLRC5.

  • ポジティブ・コントロール
    • Human spleen tissue.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab117624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 204 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能
    Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.
  • 組織特異性
    Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate.
  • 配列類似性
    Belongs to the NLRP family.
    Contains 26 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Caterpiller protein 16.1 antibody
    • CLR16.1 antibody
    • FLJ21709 antibody
    • FLJ39711 antibody
    • NLR family, CARD domain containing 5 antibody
    • NLR family, CARD-containing 5 antibody
    • NLR family, caspase recruitment domain-containing 5 antibody
    • NLRC5 antibody
    • NLRC5_HUMAN antibody
    • NOD-like receptor C5 antibody
    • NOD27 antibody
    • NOD4 antibody
    • Nucleotide-binding oligomerization domain protein 27 antibody
    • Nucleotide-binding oligomerization domain protein 4 antibody
    • nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5 antibody
    • nucleotide-binding oligomerization domains 27 antibody
    • OTTHUMP00000164675 antibody
    • Protein Caterpiller 16.1 antibody
    • Protein NLRC5 antibody
    see all

Anti-NLRC5 antibody 画像

  • ab117624, at 5 µg/ml, staining NLRC5 in Formalin-fixed, Paraffin-embedded Human Spleen tissue by Immunohistochemistry.

Anti-NLRC5 antibody (ab117624) 使用論文

This product has been referenced in:
  • Li X  et al. NLRC5 expression in tumors and its role as a negative prognostic indicator in stage III non-small-cell lung cancer patients. Oncol Lett 10:1533-1540 (2015). Read more (PubMed: 26622704) »

See 1 Publication for this product

Product Wall

Abreviews
Abcam has not validated the combination of species/application used in this Abreview.
Application
Western blot
Sample
Mouse Cell lysate - whole cell (BMDM)
Gel Running Conditions
Reduced Denaturing (4-15)
Loading amount
30 µg
Treatment
+/- IFNg
Specification
BMDM
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
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投稿 Jul 18 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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