The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 204 kDa.
Use at an assay dependent concentration.
Use a concentration of 5 µg/ml.
機能Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.
組織特異性Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate.
配列類似性Belongs to the NLRP family. Contains 26 LRR (leucine-rich) repeats. Contains 1 NACHT domain.