製品の概要

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab55781 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報
    WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
    • 組織特異性
      Highly expressed in the prostate and, at a lower level, in the testis.
    • 配列類似性
      Belongs to the NK-3 homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • 翻訳後修飾
      Ubiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.
    • 細胞内局在
      Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BAPX 2 antibody
      • BAPX2 antibody
      • Homeobox protein NK-3 homolog A antibody
      • Homeobox protein Nkx 3.1 antibody
      • Homeobox protein Nkx-3.1 antibody
      • Homeobox protein Nkx3.1 antibody
      • NK homeobox (Drosophila) family 3 A antibody
      • NK homeobox family 3 A antibody
      • NK homeobox, family 3, member A antibody
      • NK3 homeobox 1 antibody
      • NK3 transcription factor homolog A antibody
      • NK3 transcription factor related locus 1 antibody
      • NKX 3 antibody
      • Nkx 3.1 antibody
      • NKX 3A antibody
      • NKX3 1 antibody
      • NKX3 antibody
      • Nkx3-1 antibody
      • NKX3.1 antibody
      • Nkx3.1, mouse, homolog of antibody
      • NKX31_HUMAN antibody
      • NKX3A antibody
      see all

    画像



    • Predicted band size : 26 kDa
      Nkx3.1 antibody (ab55781) at 1ug/lane + NIH/3T3 cell lysate at 25ug/lane.

    プロトコール

    参考文献

    This product has been referenced in:
    • Daniels G  et al. TBLR1 as an androgen receptor (AR) coactivator selectively activates AR target genes to inhibit prostate cancer growth. Endocr Relat Cancer 21:127-42 (2014). WB ; Human . Read more (PubMed: 24243687) »
    • Bohmer M  et al. Structural Analysis of microRNA-Target Interaction by Sequential Seed Mutagenesis and Stem-Loop 3' RACE. PLoS One 8:e81427 (2013). WB ; Human . Read more (PubMed: 24282594) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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