製品の概要

  • 製品名Anti-NKIRAS2 antibody
    NKIRAS2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to NKIRAS2
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-192 of Human NKIRAS2

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57303 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
    • 組織特異性Widely expressed.
    • 配列類似性Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
    • ドメインIn contrast to other members of the Ras family, the members of the KappaB-Ras subfamily do not contain the conserved Gly and Gln residues in positions 13 and 65, which are replaced by Ala and Leu residues, respectively, and are therefore similar to the constitutively active forms of oncogenic forms of Ras. This suggests that members of this family are clearly different from other small GTPases proteins.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZP434N1526 antibody
      • I kappa B interacting Ras like protein 2 antibody
      • I-kappa-B-interacting Ras-like protein 2 antibody
      • Kappa B Ras protein 2 antibody
      • Kappa B-Ras protein 2 antibody
      • KappaB Ras2 antibody
      • KappaB-Ras2 antibody
      • KBRAS 2 antibody
      • KBRAS2 antibody
      • KBRS2_HUMAN antibody
      • MGC74742 antibody
      • NF kappa B inhibitor interacting Ras like protein 2 antibody
      • NF-kappa-B inhibitor-interacting Ras-like protein 2 antibody
      • NFKB inhibitor interacting Ras like 2 antibody
      • NFKB inhibitor interacting Ras like protein 2 antibody
      • NKIRAS 2 antibody
      • NKIRAS2 antibody
      see all

    Anti-NKIRAS2 antibody 画像

    • NKIRAS2 antibody (ab57303) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.


    • Predicted band size : 22 kDa
      NKIRAS2 antibody (ab57303) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-NKIRAS2 antibody (ab57303) 使用論文

    ab57303 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57303.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"