製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名184C278
  • アイソタイプIgG1
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab13666 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 23 kDa.

ターゲット情報

  • 機能Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
  • 組織特異性Widely expressed.
  • 配列類似性Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
  • ドメインIn contrast to other members of the Ras family, the members of the KappaB-Ras subfamily do not contain the conserved Gly and Gln residues in positions 13 and 65, which are replaced by Leu residues, and are therefore similar to the constitutively active forms of oncogenic forms of Ras. This suggests that members of this family are clearly different from other small GTPases proteins.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2400004O09Rik antibody
    • I kappa B interacting Ras like protein 1 antibody
    • I-kappa-B-interacting Ras-like protein 1 antibody
    • Kappa B Ras 1 antibody
    • Kappa B Ras protein 1 antibody
    • Kappa B-Ras protein 1 antibody
    • KappaB Ras1 antibody
    • KappaB-Ras1 antibody
    • KBRAS 1 antibody
    • KBRAS1 antibody
    • KBRS1_HUMAN antibody
    • NF kappa B inhibitor interacting Ras like protein 1 antibody
    • NF-kappa-B inhibitor-interacting Ras-like protein 1 antibody
    • NFKB inhibitor interacting Ras like 1 antibody
    • NFKB inhibitor interacting Ras like protein 1 antibody
    • NKIRAS 1 antibody
    • nkiras1 antibody
    see all

Anti-NKIRAS1 antibody [184C278] (ab13666) 使用論文

ab13666 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab13666.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"