製品の概要

  • 製品名Anti-NIR1 antibody
    NIR1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to NIR1
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide:

    SWARGPPKFESVP

    , corresponding to C terminal amino acids 962-974 of Human NIR1 (UniProt ID: Q9BZ71).

  • ポジティブ・コントロール
    • Human brain cortex

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115593 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/16000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions.
  • 組織特異性Detected in brain and spleen, and at low levels in ovary.
  • 関連疾患Defects in PITPNM3 are the cause of cone-rod dystrophy type 5 (CORD5) [MIM:600977]. CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa.
  • 配列類似性Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
    Contains 1 DDHD domain.
  • 細胞内局在Endomembrane system.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CORD5 antibody
    • Membrane associated phosphatidylinositol transfer protein 3 antibody
    • membrane-associated 3 antibody
    • Membrane-associated phosphatidylinositol transfer protein 3 antibody
    • MGC157740 antibody
    • MGC157741 antibody
    • NIR 1 antibody
    • NIR-1 antibody
    • NIR1 antibody
    • Phosphatidylinositol transfer protein antibody
    • Phosphatidylinositol transfer protein, membrane-associated 3 antibody
    • PITM3_HUMAN antibody
    • PITPnm 3 antibody
    • PITPNM antibody
    • PITPNM family member 3 antibody
    • Pitpnm3 antibody
    • PYK2 N terminal domain interacting receptor 1 antibody
    • Pyk2 N-terminal domain-interacting receptor 1 antibody
    • RDGBA3 antibody
    • Retinal degeneration B alpha 3 antibody
    see all

Anti-NIR1 antibody 画像

  • ab115593, at 5 µg/ml, staining NIR1 in formalin fixed, paraffin embedded Human brain, cortex by Immunohistochemistry. After incubation with the primary antibody, slides were incubated with biotinylated anti-goat secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Anti-NIR1 antibody (ab115593) 使用論文

ab115593 has not yet been referenced specifically in any publications.

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