製品の概要

  • 製品名Anti-NGF antibody
    NGF 一次抗体 製品一覧
  • 製品の詳細
    Sheep polyclonal to NGF
  • 特異性Specificity was demonstrated by ELISA which showed there was less than 1% cross-reactivity against recombinant human Brain Derived Neurotrophic Factor (BDNF) and Neurotrophin 4 (NT4). There was approximately 2% cross reactivity with Neurotrophin 3 (NT3).
  • アプリケーション適用あり: WB, ELISA, Inhibition Assay, IHC-Frmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Native mouse salivary gland NGF with a purity greater than 95%.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab49205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 10 µg/ml. Predicted molecular weight: 27 kDa.
ELISA Use a concentration of 1 - 10 µg/ml.
Inhibition Assay Use at an assay dependent dilution. Use neat for in vivo animal studies at 2-10 ug/g body weight (ED50).
IHC-Fr Use a concentration of 1 - 10 µg/ml.

ターゲット情報

  • 機能Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
  • 関連疾患Neuropathy, hereditary sensory and autonomic, 5
  • 配列類似性Belongs to the NGF-beta family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Beta nerve growth factor antibody
    • Beta NGF antibody
    • Beta-nerve growth factor antibody
    • Beta-NGF antibody
    • HSAN5 antibody
    • MGC161426 antibody
    • MGC161428 antibody
    • Nerve growth factor (beta polypeptide) antibody
    • Nerve growth factor antibody
    • Nerve growth factor beta antibody
    • Nerve growth factor beta polypeptide antibody
    • Nerve growth factor beta subunit antibody
    • NGF antibody
    • NGF_HUMAN antibody
    • NGFB antibody
    • NID67 antibody
    see all

Anti-NGF antibody (ab49205) 使用論文

This product has been referenced in:
  • Nakano Y  et al. A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation. PLoS Genet 9:e1003364 (2013). IHC-Fr ; Human . Read more (PubMed: 23593010) »
  • Kawakami M  et al. Functional transplantation of salivary gland cells differentiated from mouse early ES cells in vitro. Hum Cell 26:80-90 (2013). Read more (PubMed: 23681939) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab49205.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"