Mouse, Hamster, Xenopus laevis
Recombinant fragment corresponding to amino acids 291-390 (DDVFYPGTGR SPAAGSSQSS GWPNDVDAGP ASLKKSGKLD FCSALSSQGS SPRMAFTHHP LPVLAGVRPG SPRATASALH FPSTSIIQQS SPYFTHPTIR) of human NFIX (NP_002492) with a proprietary tag.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 55 kDa.
Use at an assay dependent dilution.
機能Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
配列類似性Belongs to the CTF/NF-I family. Contains 1 CTF/NF-I DNA-binding domain.
Ferenczy MW et al. Clonal immortalized human glial cell lines support varying levels of JC virus infection due to differences in cellular gene expression. J Neuroimmune Pharmacol8:1303-19 (2013).
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