製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Neurturin
  • アプリケーション
    適用あり: ELISA, IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Recombinant full length protein (Human)

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: None
    Constituents: Whole serum
  • 精製度
    Whole antiserum
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab49203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
IHC-P
IHC-Fr
  • 追加情報
    1 site ELISA: 1/5000.
    IHC-Fr: 1/2000.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
    • 関連疾患
      Defects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
    • 配列類似性
      Belongs to the TGF-beta family. GDNF subfamily.
    • 細胞内局在
      Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Neurturin antibody
      • Neurturin precursor antibody
      • NRTN antibody
      • NRTN_HUMAN antibody
      • NTN antibody
      • prepro-neurturin antibody
      see all

    Anti-Neurturin antibody 画像

    • ab49203 staining Neurturin in Human cochleae tissue sections by Immunohistochemistry. Samples were incubated with primary antibody (1/100) for 20 hours at 4°C. Positive Neuturin immunostaining was found in the spiral ganglion cell bodies and nerve fibers. The circle indicates peripheral nerve processes, arrows point to the nerve bundles of the central processes. 

    プロトコール

    Anti-Neurturin antibody (ab49203) 使用論文

    This product has been referenced in:
    • Liu W  et al. Possible role of gap junction intercellular channels and connexin 43 in satellite glial cells (SGCs) for preservation of human spiral ganglion neurons : A comparative study with clinical implications. Cell Tissue Res 355:267-78 (2014). IHC . Read more (PubMed: 24241398) »
    • Liu W & Rask-Andersen H Immunohistological analysis of neurturin and its receptors in human cochlea. Auris Nasus Larynx N/A:N/A (2013). IHC-P, IHC-Fr ; Human . Read more (PubMed: 24139947) »

    See all 2 Publications for this product

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    There are currently no Abreviews or Questions for ab49203.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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