Anti-Neurotrophin 4 抗体 (ab6205)

製品の概要

  • 製品名Anti-Neurotrophin 4 antibody
    Neurotrophin 4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Neurotrophin 4
  • 特異性Less than 1% cross reactivity against NGF, BDNF and NT3 by dot blot. Cross reactivity: Known to react with human NT4. Not yet tested against other species.
  • アプリケーション適用あり: Dot blot, ELISA, IHC-Fr, Neutralising, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein (Human).

  • 特記事項The concentrations of NT4 are generally very low in most tissues. A good positive control is neonatal testes of rat (Zhang et al, 1999). This antibody has been shown useful for quantitative ELISA, immunohistochemistry of lesioned brain as well as for western blot and inhibition of biological activity

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab6205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Dot blot
ELISA
IHC-Fr
Neutralising
WB
  • 追加情報Immunohistochemistry: 1-2 ug/ml
    Western Blot: 1-2 ug/ml
    Immunoblot: 1-2 ug/ml
    1 site ELISA: 0.5 ug/ml
    Biological Inhibition: 2-10 ug/ml (ED50)
  • ターゲット情報

    • 機能Target-derived survival factor for peripheral sensory sympathetic neurons.
    • 組織特異性Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
    • 関連疾患Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.
    • 配列類似性Belongs to the NGF-beta family.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • GLC10 antibody
      • GLC1O antibody
      • Neurotrophic factor 4 antibody
      • Neurotrophic factor 5 antibody
      • Neurotrophin 4/5 antibody
      • Neurotrophin 5 (neurotrophin 4/5) antibody
      • Neurotrophin 5 antibody
      • Neurotrophin-4 antibody
      • Neurotrophin-5 antibody
      • Neutrophic factor 4 antibody
      • Neutrophic factor 5 antibody
      • NT 4 antibody
      • NT 4/5 antibody
      • NT 5 antibody
      • NT-4 antibody
      • NT-5 antibody
      • NT4 antibody
      • NT4/5 antibody
      • NT4P antibody
      • NT5 antibody
      • NTF4 antibody
      • NTF4_HUMAN antibody
      • NTF5 antibody
      see all

    Anti-Neurotrophin 4 antibody (ab6205) 使用論文

    ab6205 has not yet been referenced specifically in any publications.

    Product Wall

    ab6204 and ab6205 are both suitable for detecting neurotrophin 4/5 using immunohistochemistry, but we recommend ab6205 which is the affinity purified version of ab6204 and therefore likely to give less background.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"