Anti-Neuroserpin 抗体 (ab32901)

製品の概要

  • 製品名Anti-Neuroserpin antibody
    Neuroserpin 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Neuroserpin
  • アプリケーション適用あり: ICC/IF, IHC-FoFr, WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Chicken, Chimpanzee
  • 免疫原

    Synthetic peptide:

    TMNTSGHDFEEL

    (Human)(C-terminal)

  • ポジティブ・コントロール
    • Human brain lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab32901 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration.
IHC-FoFr Use at an assay dependent concentration.
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 48 kDa.
ELISA 1/32000.

ターゲット情報

  • 機能Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
  • 組織特異性Predominantly expressed in the brain.
  • 関連疾患Defects in SERPINI1 are the cause of familial encephalopathy with neuroserpin inclusion bodies (FEN1B) [MIM:604218]. FEN1B is characterized clinically as an autosomal dominantly inherited dementia, histologically by unique neuronal inclusion bodies and biochemically by polymers of neuroserpin.
  • 配列類似性Belongs to the serpin family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp781N13156 antibody
    • Neuroserpin antibody
    • NEUS_HUMAN antibody
    • Peptidase inhibitor 12 antibody
    • PI-12 antibody
    • PI12 antibody
    • Protease inhibitor 12 antibody
    • Serine or cysteine proteinase inhibitor clade I (neuroserpin) member 1 antibody
    • Serine or cysteine proteinase inhibitor clade I member 1 antibody
    • Serpin I1 antibody
    • Serpin peptidase inhibitor clade I (neuroserpin) member 1 antibody
    • SERPINI1 antibody
    see all

Anti-Neuroserpin antibody 画像

  • Anti-Neuroserpin antibody (ab32901) at 1 µg/ml + Human Brain lysate (35µg protein in RIPA buffer)

    Predicted band size : 48 kDa

Anti-Neuroserpin antibody (ab32901) 使用論文

ab32901 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (PFA perfusion fixed frozen sections)
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 2% · Temperature: 25°C
Sample Mouse Cell (brain hemisphere coronal sections)
Specification brain hemisphere coronal sections
Permeabilization Yes - 0.1% Triton-X
Fixative Paraformaldehyde
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投稿 Jul 05 2013

Thank you for your enquiry. The sequence comparison shows only 33% identity between the ab32901 immunogenic peptide and mouse serpini2. The file for this comparison is found at this link for the next 24 hours: http://www.ebi.ac.uk/cgi-bin/clust...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"