製品の概要

  • 製品名Anti-Neuroserpin antibody [1D10]
    Neuroserpin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [1D10] to Neuroserpin
  • アプリケーション適用あり: Sandwich ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length mature protein, corresponding to amino acids 17-410 of Human Neuroserpin with 26kDa proprietary tag (AAH18043).

  • ポジティブ・コントロール
    • HeLa cell lysate;, Hman Brain cortex tissue; recombinant protein.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125097 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Sandwich ELISA Use at an assay dependent concentration.
WB 1/500 - 1/1000. Predicted molecular weight: 46 kDa.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
  • 組織特異性Predominantly expressed in the brain.
  • 関連疾患Defects in SERPINI1 are the cause of familial encephalopathy with neuroserpin inclusion bodies (FEN1B) [MIM:604218]. FEN1B is characterized clinically as an autosomal dominantly inherited dementia, histologically by unique neuronal inclusion bodies and biochemically by polymers of neuroserpin.
  • 配列類似性Belongs to the serpin family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp781N13156 antibody
    • Neuroserpin antibody
    • NEUS_HUMAN antibody
    • Peptidase inhibitor 12 antibody
    • PI-12 antibody
    • PI12 antibody
    • Protease inhibitor 12 antibody
    • Serine or cysteine proteinase inhibitor clade I (neuroserpin) member 1 antibody
    • Serine or cysteine proteinase inhibitor clade I member 1 antibody
    • Serpin I1 antibody
    • Serpin peptidase inhibitor clade I (neuroserpin) member 1 antibody
    • SERPINI1 antibody
    see all

Anti-Neuroserpin antibody [1D10] 画像

  • Anti-Neuroserpin antibody [1D10] (ab125097) at 1/500 dilution + HeLa cell lysate

    Predicted band size : 46 kDa
  • ab125097, at 5 µg/ml, staining Neuroserpin in Formalin-fixed, Paraffin-embedded Human brain cortex tissue by Immunohistochemistry
  • Using ab125097 as a capture antibody, the detection limit for recombinant proprietary tagged Neuroserpin is approximately 0.3ng/ml.

Anti-Neuroserpin antibody [1D10] (ab125097) 使用論文

ab125097 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"