This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Anti-Neuron navigator 1 抗体 (ab32209)


  • 製品名Anti-Neuron navigator 1 antibody
    Neuron navigator 1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Neuron navigator 1

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • 特異性We have tested Rabbit polyclonal to Neuron navigator 1 (ab32209) in Western Blot on adult mouse heart lysate, we do not detect the full length protein (202 kDa) in this lysate, however we do detect two fragments corresponding to Neuron navigator 1 (58 kDa and 64 kDa; data not shown). As Neuron navigator 1 protein is primarily expressed in development, we would appreciate any testing feedback in more appropriate positive control tissue.
  • 種交差性

    交差が予測される動物種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1850 to the C-terminus of Mouse Neuron navigator 1.

    (Peptide available as ab32208.)



  • 追加情報This antibody gave a positive result in ELISA against the immunizing peptide (ab32208).
    Not yet tested in other applications.
  • ターゲット情報

    • 関連性The development of the nervous system (NS) requires the coordinated migration of multiple waves of neurons and subsequent processes of neurite maturation, both involving selective guidance mechanisms. In Caenorhabditis elegans, unc-53 codes for a new multidomain protein involved in the directional migration of a subset of cells. We describe here the first functional characterization of the mouse homologue, mouse Neuron navigator 1 (mNAV1) expression is primarily restricted to the CNS during development. mNAV1 is a microtubules associated protein. The abolition of mNAV1 causes loss of directionality in the leading processes of pontine-migrating cells, providing evidence for a role of mNAV1 in mediating (Netrin1-induced) directional migration.
    • 細胞内局在Cytoplasm › cytoskeleton. Note: Associates with a subset of microtubule plus ends. Enriched in neuronal growth cone.
    • 参照データベース
    • 別名
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      • mNav1 antibody
      • mouse Nav1 antibody
      • Nav 1 antibody
      • Nav1 antibody
      • neuron navigator 1 antibody
      • POMFIL 3 antibody
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    Anti-Neuron navigator 1 antibody (ab32209) 使用論文

    ab32209 has not yet been referenced specifically in any publications.

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