製品の概要

  • 製品名
    Anti-Neuroligin 2 antibody
    Neuroligin 2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Neuroligin 2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Rat, Human
    交差が予測される動物種: Mouse, Dog
  • 免疫原

    Synthetic peptide:

    NPPDTDIRDPGKK

    , corresponding to internal sequence amino acids 165-177 of Human Neuroligin 2 (NP_065846.1).

  • ポジティブ・コントロール
    • Human Pancreas lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab77595 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77595 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 91 kDa (predicted molecular weight: 91 kDa). An additional band of unknown identity was also consistently observed at 50kDa. This band was successfully blocked by incubation with the immunising peptide.

ターゲット情報

  • 関連性
    Neuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 2 is exclusively localized to inhibitory synapses in rat brain and dissociated neurons. In immature neurons, neuroligin 2 is found at synapses and also at GABAA receptor aggregates that are not facing presynaptic termini.
  • 細胞内局在
    Cell Membrane
  • 参照データベース
  • 別名
    • KIAA1366 antibody
    • MGC67386 antibody
    • NL2 antibody
    • NLGN2 antibody
    • Ortholog of human and rat neuroligin 2 NLGN2 antibody
    • OTTHUMP00000135277 antibody
    • OTTMUSP00000006214 antibody
    • RP23-422L16.24 antibody
    see all

画像

  • Anti-Neuroligin 2 antibody (ab77595) at 2 µg/ml + Human Pancrease lysate (in RIPA buffer) at 35 µg

    Predicted band size : 91 kDa

    Primary incubation was 1 hour.

    Detected by chemiluminescence.

プロトコール

参考文献

ab77595 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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