This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

製品の概要

製品の特性

アプリケーション

  • 追加情報
    This antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:4,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses.
    • 組織特異性
      Expressed in the blood vessel walls (at protein level).
    • 配列類似性
      Belongs to the type-B carboxylesterase/lipase family.
    • 細胞内局在
      Cell membrane. Cell junction > synapse. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities.
    • Information by UniProt
    • 参照データベース
    • 別名
      • NLG 1 antibody
      • KIAA1070 antibody
      • MGC45115 antibody
      • Neuroligin-1 antibody
      • NL1 antibody
      • NLG1 antibody
      • Nlgn1 antibody
      • NLGN1_HUMAN antibody
      see all

    参考文献

    ab36131 has not yet been referenced specifically in any publications.

    レビューと Q&A

    Abcam has not validated the combination of species/application used in this Abreview.
    Application
    Immunocytochemistry
    Sample
    Rat Cultured Cells (neurons)
    Specification
    neurons
    Fixative
    Methanol
    Permeabilization
    No
    Blocking step
    BSA as blocking agent for 15 minute(s) · Concentration: 0.3% · Temperature: 20°C
    Username

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    Verified customer

    投稿 Feb 07 2011

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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