追加情報This antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:4,000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses.
組織特異性Expressed in the blood vessel walls (at protein level).
配列類似性Belongs to the type-B carboxylesterase/lipase family.
細胞内局在Cell membrane. Cell junction > synapse. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities.