Anti-Neurokinin 3 Receptor NK3 抗体 (ab124025)

製品の概要

  • 製品名
    Anti-Neurokinin 3 Receptor NK3 antibody
    Neurokinin 3 Receptor NK3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Neurokinin 3 Receptor NK3
  • 特異性
    ab124025 does not recognise NK1R or NK2R.
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    An 18 amino acid peptide from near the center of Human Neurokinin 3 Receptor NK3.

  • ポジティブ・コントロール
    • Human brain tissue; RAW 264.7 whole cell lysate
  • 特記事項
    This product should be stored undiluted.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
  • バッファー
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Protein A purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab124025 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 52 kDa).Can be blocked with Neurokinin 3 Receptor NK3 peptide (ab176411).
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
  • 関連疾患
    Hypogonadotropic hypogonadism 11 with or without anosmia
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • 翻訳後修飾
    The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC148060 antibody
    • MGC148061 antibody
    • Neurokinin B receptor antibody
    • Neurokinin beta receptor antibody
    • Neuromedin K Receptor antibody
    • Neuromedin-K receptor antibody
    • NK 3 receptor antibody
    • NK 3R antibody
    • NK-3 receptor antibody
    • NK-3R antibody
    • NK3 receptor antibody
    • NK3R antibody
    • NK3R_HUMAN antibody
    • NKR antibody
    • TAC 3R antibody
    • TAC3R antibody
    • TAC3RL antibody
    • Tachykinin receptor 3 antibody
    • TACR 3 antibody
    • Tacr3 antibody
    see all

Anti-Neurokinin 3 Receptor NK3 antibody 画像

  • Lane 1 : Anti-Neurokinin 3 Receptor NK3 antibody (ab124025) at 0.5 µg/ml
    Lane 2 : Anti-Neurokinin 3 Receptor NK3 antibody (ab124025) at 2 µg/ml

    Lane 1 : RAW 264.7 whole cell lysate
    Lane 2 : RAW 264.7 whole cell lysate


    Predicted band size : 52 kDa
    Observed band size : 46 kDa (why is the actual band size different from the predicted?)
  • ab124025, at 5µg/ml, staining Neurokinin 3 Receptor NK3 in paraffin-embedded Human brain tissue by Immunohistochemistry.

Anti-Neurokinin 3 Receptor NK3 antibody (ab124025) 使用論文

This product has been referenced in:
  • Vielma AH & Schmachtenberg O Electrophysiological fingerprints of OFF bipolar cells in rat retina. Sci Rep 6:30259 (2016). IHC-P ; Rat . Read more (PubMed: 27457753) »

See 1 Publication for this product

Product Wall

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Human Tissue sections (Nasal mucosa)
Antigen retrieval step
None
Permeabilization
No
Specification
Nasal mucosa
Blocking step
Serum as blocking agent for 45 minute(s) · Concentration: 5 · Temperature: RT°C
Fixative
Zamboni
Username

Mr. Duc Dung Le

Verified customer

投稿 Apr 29 2015

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Mouse Tissue sections (Brain)
Antigen retrieval step
None
Specification
Brain
Blocking step
Serum as blocking agent for 45 minute(s) · Concentration: 5% · Temperature: RT°C
Username

Mr. Duc Dung Le

Verified customer

投稿 Apr 29 2015

Thank you for taking the time to complete our questionnaires and contact us. I am sorry to hearthe customer has had difficulty obtaining satisfactory results from these antibodies.

The details you have kindly provided will enable us to inves...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録