製品の概要

  • 製品名Anti-Netrin 1 antibody
    Netrin 1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Netrin 1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Zebrafish
    交差が予測される動物種: Rat, Human, Pig, Xenopus laevis
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Mouse Netrin 1.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Mouse Fetus (14 Day Old) Tissue Lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab78854 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 68 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
    • 組織特異性Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas.
    • 配列類似性Contains 3 laminin EGF-like domains.
      Contains 1 laminin N-terminal domain.
      Contains 1 NTR domain.
    • 細胞内局在Secreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • 参照データベース
    • 別名
      • epididymis tissue protein Li 131P antibody
      • NET1_HUMAN antibody
      • Netrin 1, mouse, homolog of antibody
      • Netrin 1-like antibody
      • Netrin-1 antibody
      • Netrin1 antibody
      • Ntn 1 antibody
      • NTN 1L antibody
      • NTN1 antibody
      • NTN1L antibody
      • Unc6 antibody
      see all

    Anti-Netrin 1 antibody 画像

    • Anti-Netrin 1 antibody (ab78854) at 1 µg/ml + Mouse Fetus (14 Day Old) Tissue Lysate at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 68 kDa
      Observed band size : 72 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 3 minutes

    Anti-Netrin 1 antibody (ab78854) 使用論文

    This product has been referenced in:
    • Liao SJ  et al. Netrin-1 rescues neuron loss by attenuating secondary apoptosis in ipsilateral thalamic nucleus following focal cerebral infarction in hypertensive rats. Neuroscience 231:225-32 (2013). Read more (PubMed: 23232257) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab78854.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"