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RabMAb

Anti-NETO2 抗体 [EPR3497] (ab109288)

製品の概要

  • 製品名
    Anti-NETO2 antibody [EPR3497]
    NETO2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR3497] to NETO2
  • アプリケーション
    適用あり: WB, IPmore details
    適用なし: Flow Cyt,ICC or IHC-P
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in human NETO2

  • ポジティブ・コントロール
    • Human cerebellum, SH-SY5Y and Human brain lysates; Mouse and Rat brain lysates.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファー
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度
    Tissue culture supernatant
  • ポリ/モノ
    モノクローナル
  • クローン名
    EPR3497
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab109288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 60 kDa.
IP 1/10 - 1/100.
  • 追加情報
    Is unsuitable for Flow Cyt,ICC or IHC-P.
  • ターゲット情報

    • 機能
      Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission.
    • 配列類似性
      Contains 2 CUB domains.
      Contains 1 LDL-receptor class A domain.
    • 翻訳後修飾
      N-glycosylated.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Brain specific transmembrane protein antibody
      • Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2 antibody
      • Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2 antibody
      • BTCL2 antibody
      • FLJ10430 antibody
      • FLJ14724 antibody
      • FLJ90456 antibody
      • NEOT2 antibody
      • NETO 2 antibody
      • Neto2 antibody
      • NETO2_HUMAN antibody
      • Neuropilin (NRP) and tolloid (TLL) like 2 antibody
      • Neuropilin and tolloid like protein 2 antibody
      • Neuropilin and tolloid-like protein 2 antibody
      see all

    画像

    • All lanes : Anti-NETO2 antibody [EPR3497] (ab109288) at 1/1000 dilution

      Lane 1 : Human cerebellum lysates
      Lane 2 : SH-SY5Y cell lysates
      Lane 3 : Human brain lysates

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 60 kDa
    • All lanes : Anti-NETO2 antibody [EPR3497] (ab109288) at 1/1000 dilution

      Lane 1 : mouse brain lysates
      Lane 2 : rat brain lysates

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 60 kDa

    参考文献

    This product has been referenced in:
    • Vernon CG & Swanson GT Neto2 assembles with kainate receptors in DRG neurons during development and modulates neurite outgrowth in adult sensory neurons. J Neurosci N/A:N/A (2017). WB . Read more (PubMed: 28235897) »
    • Hu L  et al. Upregulation of NETO2 expression correlates with tumor progression and poor prognosis in colorectal carcinoma. BMC Cancer 15:1006 (2015). WB ; Human . Read more (PubMed: 26699544) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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