製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to NET1
  • アプリケーション
    適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Dog, Human
    交差が予測される動物種: Chicken, Cow, Cynomolgus monkey, Orangutan
  • 免疫原

    Synthetic peptide:

    DKLEYLDEKQRDPR,

    Human, from the internal region of the protein sequence according to NP_005854.2; NP_001040625.1

  • ポジティブ・コントロール
    • Breast tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab79006 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/16000.
IHC-P Use a concentration of 2.5 µg/ml.

ターゲット情報

  • 機能
    Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
  • 組織特異性
    Widely expressed.
  • 配列類似性
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
  • 細胞内局在
    Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ARHG8_HUMAN antibody
    • ARHGEF8 antibody
    • GLYT2 antibody
    • Guanine nucleotide regulatory protein oncogene antibody
    • MGC114559 antibody
    • MGC127767 antibody
    • MGC53602 antibody
    • mNET1 antibody
    • Net1 antibody
    • NET1A antibody
    • Neuroepithelial cell transforming gene 1 antibody
    • Neuroepithelial cell-transforming gene 1 protein antibody
    • p65 Net1 proto oncogene antibody
    • Proto-oncogene p65 Net1 antibody
    • Rho guanine nucleotide exchange factor 8 antibody
    • Rho guanine nucleotide exchange factor GEF 8 antibody
    see all

画像

  • ab79006 at 2.5µg/ml staining NET1 in breast tissue.

プロトコール

参考文献

ab79006 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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