製品の概要

  • 製品名Anti-NELFe antibody
    NELFe 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NELFe
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region between residue 330 and 380 of human NELFe (NP_002895.3)

  • ポジティブ・コントロール
    • Human Breast Carcinoma, human Placenta

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab84986 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.
    • 組織特異性Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas.
    • 配列類似性Belongs to the RRM NELF-E family.
      Contains 1 RRM (RNA recognition motif) domain.
    • ドメインThe RRM domain interacts with RNA, and is essential for NELF complex function. It is however not required for the NELF complex formation.
    • 翻訳後修飾Sumoylated.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Major histocompatibility complex gene RD antibody
      • Negative elongation factor E antibody
      • Negative elongation factor polypeptide E antibody
      • NELF e antibody
      • NELF-E antibody
      • Nelfe antibody
      • NELFE_HUMAN antibody
      • Nuclear protein antibody
      • RD antibody
      • RD protein antibody
      • RD RNA binding protein antibody
      • RDP antibody
      • RNA-binding protein RD antibody
      see all

    Anti-NELFe antibody 画像

    • ab84986 at 1/250 dilution staining NELFe in human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
    • ab84986 at 1/250 dilution staining NELFe in human placenta by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

    Anti-NELFe antibody (ab84986) 使用論文

    ab84986 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab84986.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"