製品の概要

  • 製品名Anti-NELF antibody
    NELF 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NELF
  • 特異性NELF recognises both the 263 aa and 528 aa isoform.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    A region within synthetic peptide: SDPTPMKADT SHDSRDSSDL QSSHCTLDEA FEDLDWDTEK GLEAVACDTE, corresponding to internal sequence amino acids 289-338 of Human NELF

  • ポジティブ・コントロール
    • HepG2 cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab58752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 5 µg/ml. Detects a band of approximately 29 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Couples NMDA receptor signaling to the nucleus. Influences outgrowth of olfactory axons and migration of LHRH neurons.
  • 組織特異性Highly expressed in adult and fetal brain, testis and kidney.
  • 関連疾患Defects in NELF may be associated with idiopathic hypogonadotropic hypogonadism (IHH) [MIM:146110]. IHH is defined as a deficiency of the pituitary secretion of follicle-stimulating hormone and luteinizing hormone, which results in the impairment of pubertal maturation and of reproductive function.
  • 細胞内局在Cell membrane. Nucleus. Found on the outside of the LHRH cell membrane and axons projecting from the olfactory pit and epithelium. Myristoylation is a prerequisite for extranuclear localization.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Nasal embryonic LHRH factor antibody
    • Nasal embryonic luteinizing hormone releasing hormone factor antibody
    • Nasal embryonic luteinizing hormone-releasing hormone factor antibody
    • Nelf antibody
    • NELF_HUMAN antibody
    see all

Anti-NELF antibody 画像

Anti-NELF antibody (ab58752) 使用論文

ab58752 has not yet been referenced specifically in any publications.

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