製品の概要

  • 製品名Anti-NEK9 antibody
    NEK9 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NEK9
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide: GGGGGEEEDS QQESETPDPS GGFRGTMEAD RGMEGLISPT EAMGNSNGAS , corresponding to internal sequence amino acids 756-805 of Human NEK9 (NP_149107)

  • ポジティブ・コントロール
    • THP-1 cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab89853 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 107 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
  • 組織特異性Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts.
  • 配列類似性Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
    Contains 1 protein kinase domain.
    Contains 6 RCC1 repeats.
  • 発生段階Expression varied mildly across the cell cycle, with highest expression observed in G1 and stationary-phase cells.
  • ドメインDimerizes through its coiled-coil domain.
  • 翻訳後修飾Autophosphorylated on serine and threonine residues. When complexed with FACT, exhibits markedly elevated phosphorylation on Thr-210. During mitosis, not phosphorylated on Thr-210. Phosphorylated by CDK1 in vitro.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KIAA1995 antibody
    • APUG antibody
    • DKFZp434D0935 antibody
    • LCCS10 antibody
    • MGC138306 antibody
    • MGC16714 antibody
    • NC antibody
    • NEK 9 antibody
    • Nek8 antibody
    • nek9 antibody
    • NEK9_HUMAN antibody
    • Nercc 1 kinase antibody
    • NERCC antibody
    • NERCC1 antibody
    • Nercc1 kinase antibody
    • Never in mitosis A related kinase 9 antibody
    • Never in mitosis A-related kinase 9 antibody
    • NIMA (never in mitosis gene a) related kinase 9 antibody
    • NIMA related kinase 8 antibody
    • NIMA related kinase 9 antibody
    • NIMA related kinase Nek8 antibody
    • NimA related protein kinase 9 antibody
    • NIMA-related kinase 8 antibody
    • NimA-related protein kinase 9 antibody
    • Serine/threonine protein kinase Nek9 antibody
    • Serine/threonine-protein kinase Nek9 antibody
    see all

Anti-NEK9 antibody 画像

  • Anti-NEK9 antibody (ab89853) at 1 µg/ml + THP-1 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 107 kDa

Anti-NEK9 antibody (ab89853) 使用論文

ab89853 has not yet been referenced specifically in any publications.

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