製品の概要

  • 製品名Anti-NEIL2 antibody
    NEIL2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to NEIL2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-333 of Human NEIL2

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab56577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
    • 組織特異性Detected in testis, skeletal muscle, heart, brain, placenta, lung, pancreas, kidney and liver.
    • 配列類似性Belongs to the FPG family.
      Contains 1 FPG-type zinc finger.
    • ドメインThe zinc-finger domain is important for DNA binding.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DNA glycosylase/AP lyase Neil2 antibody
      • DNA-(apurinic or apyrimidinic site) lyase Neil2 antibody
      • Endonuclease 8-like 2 antibody
      • Endonuclease VIII-like 2 antibody
      • NEH2 antibody
      • Nei endonuclease VIII like 2 (E. coli) antibody
      • Nei endonuclease VIII like 2 antibody
      • Nei homolog 2 antibody
      • Nei-like 2 antibody
      • Nei-like protein 2 antibody
      • NEI2 antibody
      • NEIL2 antibody
      • NEIL2_HUMAN antibody
      see all

    Anti-NEIL2 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab56577 NEIL2 antibody at 1ug/ml. Predicted band size of immunogen is 63 kDa

    Anti-NEIL2 antibody (ab56577) 使用論文

    ab56577 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry and your interest in our products. The tag such as glutathione-S-transferase (GST) is often used for proteins for expression and purification applications. GST tag is a 26 kDa protein which is attached to the NEIL2 recom...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"