製品の概要

  • 製品名Anti-NEI3 antibody
    NEI3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NEI3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from the internal region of Human NEI3.

  • ポジティブ・コントロール
    • COLO, HuvEc, HepG2 and HeLa cell extracts

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol, 0.88% Sodium chloride
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab110049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 68 kDa.

ターゲット情報

  • 機能Reports about DNA glycosylase activity are contradictory. A number of references report finding no DNA glycosylase activity and the protein lacks a proline residue at the N-terminus which functions as an active site residue in other members of the FPG family. However, the mouse ortholog has been shown to have both DNA glycosylase and AP lyase activities and PubMed:19170771 demonstrates AP lyase activity. Prefers single-stranded DNA or partially single-stranded DNA structures such as bubble and fork structures to double-stranded DNA in vitro. Displays a broad recognition spectrum, preferring FapyA and FapyG followed by 5-OHU, 5-PHC and 5-OHMH and then Tg and 8-oxoA. No activity on 8-oxoG detected.
  • 組織特異性Detected in thymus and testis. Expressed at higher levels in tumor tissue than in the corresponding normal tissues except for pancreas and testis where expression is higher in normal than tumor tissue.
  • 配列類似性Belongs to the FPG family.
    Contains 1 FPG-type zinc finger.
    Contains 1 RanBP2-type zinc finger.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 123 antibody
    • AI449477 antibody
    • BC034753 antibody
    • C85903 antibody
    • DNA glycosylase FPG2 antibody
    • DNA glycosylase hFPG2 antibody
    • DNA glycosylase/AP lyase Neil3 antibody
    • EC 3.2.2.- antibody
    • EC 4.2.99.18 antibody
    • Endonuclease 8-like 3 antibody
    • Endonuclease VIII-like 3 antibody
    • FGP2 antibody
    • FLJ10858 antibody
    • FPG2 antibody
    • hFPG2 antibody
    • hNEI3 antibody
    • MGC27861 antibody
    • MGC36916 antibody
    • Nei endonuclease VIII-like 3 (E. coli) antibody
    • nei endonuclease VIII-like 3 antibody
    • Nei like 3 (E. coli) antibody
    • Nei-like protein 3 antibody
    • NEIL3 antibody
    • NEIL3_HUMAN antibody
    • OTTHUMP00000218810 antibody
    • RGD1310562 antibody
    see all

Anti-NEI3 antibody 画像

  • All lanes : Anti-NEI3 antibody (ab110049) at 1/500 dilution

    Lane 1 : COLO cell extract
    Lane 2 : HuvEc cell extract
    Lane 3 : HepG2 cell extract
    Lane 4 : HeLa cell extract
    Lane 5 : HuvEc cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 68 kDa

Anti-NEI3 antibody (ab110049) 使用論文

ab110049 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"