Anti-NEI3 抗体 [2627C1b] (ab58643)


  • 製品名Anti-NEI3 antibody [2627C1b]
    NEI3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2627C1b] to NEI3
  • アプリケーション適用あり: WB, Dot Blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment (Human)


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)Purified using protein G column chromatography from culture supernatant of hybridoma culture in a medium containing bovine IgG depleted (approximately 95%) fetal bovine serum
  • ポリ/モノモノクローナル
  • クローン名2627C1b
  • アイソタイプIgG1
  • 研究分野


Our Abpromise guarantee covers the use of ab58643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Dot Blot
  • 追加情報Dot: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 68 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Reports about DNA glycosylase activity are contradictory. A number of references report finding no DNA glycosylase activity and the protein lacks a proline residue at the N-terminus which functions as an active site residue in other members of the FPG family. However, the mouse ortholog has been shown to have both DNA glycosylase and AP lyase activities and PubMed:19170771 demonstrates AP lyase activity. Prefers single-stranded DNA or partially single-stranded DNA structures such as bubble and fork structures to double-stranded DNA in vitro. Displays a broad recognition spectrum, preferring FapyA and FapyG followed by 5-OHU, 5-PHC and 5-OHMH and then Tg and 8-oxoA. No activity on 8-oxoG detected.
    • 組織特異性Detected in thymus and testis. Expressed at higher levels in tumor tissue than in the corresponding normal tissues except for pancreas and testis where expression is higher in normal than tumor tissue.
    • 配列類似性Belongs to the FPG family.
      Contains 1 FPG-type zinc finger.
      Contains 1 RanBP2-type zinc finger.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 123 antibody
      • AI449477 antibody
      • BC034753 antibody
      • C85903 antibody
      • DNA glycosylase FPG2 antibody
      • DNA glycosylase hFPG2 antibody
      • DNA glycosylase/AP lyase Neil3 antibody
      • EC 3.2.2.- antibody
      • EC antibody
      • Endonuclease 8-like 3 antibody
      • Endonuclease VIII-like 3 antibody
      • FGP2 antibody
      • FLJ10858 antibody
      • FPG2 antibody
      • hFPG2 antibody
      • hNEI3 antibody
      • MGC27861 antibody
      • MGC36916 antibody
      • Nei endonuclease VIII-like 3 (E. coli) antibody
      • nei endonuclease VIII-like 3 antibody
      • Nei like 3 (E. coli) antibody
      • Nei-like protein 3 antibody
      • NEIL3 antibody
      • NEIL3_HUMAN antibody
      • OTTHUMP00000218810 antibody
      • RGD1310562 antibody
      see all

    Anti-NEI3 antibody [2627C1b] 画像

    Anti-NEI3 antibody [2627C1b] (ab58643) 使用論文

    ab58643 has not yet been referenced specifically in any publications.

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