製品の概要

  • 製品名Anti-Necdin antibody
    Necdin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Necdin
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: WKKHSTFGDV RKLITEEFVQ MNYLKYQRVP YVEPPEYEFF WGSRASREIT KMQIMEFLAR VFKKDPQAWP SRYREALEEA RALREANPTA HYPRSSVSED , corresponding to amino acids 222-322 of Human Necdin

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab55501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 1 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences.
    • 組織特異性Almost ubiquitous. Detected in fetal brain, lung, liver and kidney; in adult heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. Not detected in peripheral blood leukocytes. In brain, restricted to post-mitotic neurons.
    • 配列類似性Contains 1 MAGE domain.
    • 細胞内局在Perikaryon. Nucleus. Neural perikarya, translocates to the nucleus of postmitotic neurons and interacts with the nuclear matrix.
    • Information by UniProt
    • 参照データベース
    • 別名
      • HsT16328 antibody
      • NDN antibody
      • NECD_HUMAN antibody
      • Necdin antibody
      • Necdin homolog antibody
      • necdin related protein antibody
      • PWCR antibody
      see all

    Anti-Necdin antibody 画像

    • Necdin antibody (ab55501) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human colon.


    • Predicted band size : 36 kDa
      Necdin antibody (ab55501) at 1ug/lane + HL-60 cell lysate at 25ug/lane.

    Anti-Necdin antibody (ab55501) 使用論文

    ab55501 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab55501.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"