製品の概要

  • 製品名Anti-NECAP1 antibody
    NECAP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NECAP1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 90-139 (RYFVIRIQDG TGRSAFIGIG FTDRGDAFDF NVSLQDHFKW VKQETEISKE) of Mouse NECAP1 protein (NP_080543).

  • ポジティブ・コントロール
    • Mouse spleen lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab112090 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 30 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Involved in endocytosis.
  • 配列類似性Belongs to the NECAP family.
  • ドメインThe WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Selective binding to the GAE domains of AP-1 or to the alpha-ear domain of AP-2 is tuned by the acidic context surrounding the motif and the properties of the second residue of the motif itself. The WXXF motif 1, which is preceded by an acidic residue and has a glycine in second position mediates specific interaction with AP-1. The WXXF motif 2, which is followed by the C-terminal carboxyl group negative charge, allows specific interaction with AP-2.
  • 細胞内局在Cytoplasmic vesicle > clathrin-coated vesicle membrane. Cell membrane. Colocalizes with AP-2 at the plasma membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Adaptin ear binding coat associated protein 1 antibody
    • Adaptin ear-binding coat-associated protein 1 antibody
    • DKFZP566B183 antibody
    • MGC131900 antibody
    • NECAP 1 antibody
    • NECAP endocytosis associated 1 antibody
    • NECAP endocytosis-associated protein 1 antibody
    • NECAP-1 antibody
    • NECAP1 antibody
    • NECP1_HUMAN antibody
    see all

Anti-NECAP1 antibody 画像

  • Anti-NECAP1 antibody (ab112090) at 1 µg/ml + Mouse spleen lysate at 10 µg

    Predicted band size : 30 kDa

Anti-NECAP1 antibody (ab112090) 使用論文

ab112090 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"