製品の概要

  • 製品名
    NECA
  • 製品の詳細
    Highly potent adenosine agonist
  • 生理活性の詳細
    Potent agonist of adenosine receptors, non-selective analog of adenosine (Ki values are 14 (A1), 20 (A2A), 330 (A2B), and 6.2 nM (A3)). Offers cardio-protection by limiting infarction in situ.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Liu Y  et al. AMP579 is revealed to be a potent A2b-adenosine receptor agonist in human 293 cells and rabbit hearts. Basic Res Cardiol 105:129-37 (2010). Read more (PubMed: 19730798) »
  • Philipp S  et al. Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade. Cardiovasc Res 70:308-14 (2006). Read more (PubMed: 16545350) »
  • Klotz KN Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch Pharmacol 362:382-91 (2000). Read more (PubMed: 11111832) »

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