製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to NDUFV1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Zebrafish
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 218 and 429 of Human NDUFV1

  • ポジティブ・コントロール
    • HepG2 whole cell lysate

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96227 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 51 kDa.

ターゲット情報

  • 機能
    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • 関連疾患
    Defects in NDUFV1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.
    Defects in NDUFV1 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
  • 配列類似性
    Belongs to the complex I 51 kDa subunit family.
  • 細胞内局在
    Mitochondrion inner membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CI 51kD antibody
    • CI-51kD antibody
    • CI51KD antibody
    • Complex I 51kD antibody
    • Complex I-51kD antibody
    • FLJ59059 antibody
    • mitochondrial antibody
    • NADH dehydrogenase (ubiquinone) flavoprotein 1 antibody
    • NADH dehydrogenase [ubiquinone] flavoprotein 1 antibody
    • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial antibody
    • NADH dehydrogenase flavoprotein 1 antibody
    • NADH ubiquinone oxidoreductase 51 kDa subunit antibody
    • NADH ubiquinone oxidoreductase antibody
    • NADH ubiquinone oxidoreductase core subunit V1 antibody
    • NADH-ubiquinone oxidoreductase 51 kDa subunit antibody
    • NDUFV 1 antibody
    • ndufv1 antibody
    • NDUV1_HUMAN antibody
    • UQOR1 antibody
    see all

画像

  • Anti-NDUFV1 antibody (ab96227) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 51 kDa

プロトコール

参考文献

ab96227 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab96227.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録