製品の概要

  • 製品名Anti-NDRG2 antibody
    NDRG2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to NDRG2
  • アプリケーション適用あり: WB, ICC/IF, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: MAELQEVQIT EEKPLLPGQT PEAAKTHSVE TPYGSVTFTV YGTPKPKRPA ILTYHDVGLN YKSCFQPLFQ FEDMQEIIQN FVRVHVDAPG MEEGAP, corresponding to amino acids 1-97 of Human NDRG2

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 41 kDa.
ICC/IF Use at an assay dependent concentration. PubMed: 23800335
IHC-P Use at an assay dependent concentration. PubMed: 23800335

ターゲット情報

  • 機能May be involved in dendritic cell and neuron differentiation. May have anti-tumor activity.
  • 組織特異性Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
  • 配列類似性Belongs to the NDRG family.
  • 発生段階Specifically expressed during dendritic cell differentiation (in vitro). Expression is low in fetal brain and increases during brain postnatal development.
  • 細胞内局在Cytoplasm. Cytoplasm > perinuclear region. Perinuclear in neurons.
  • Information by UniProt
  • 参照データベース
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Anti-NDRG2 antibody 画像



  • Predicted band size : 41 kDa
    NDRG2 antibody (ab57429) at 1ug/lane + HeLa cell lysate at 25ug/lane.

Anti-NDRG2 antibody (ab57429) 使用論文

This product has been referenced in:
  • Wu Z  et al. Adenovirus-mediated NDRG2 inhibits the proliferation of human renal cell carcinoma cell line OS-RC-2 in vitro. Cell Biochem Biophys 70:593-600 (2014). Human . Read more (PubMed: 24839115) »
  • Cao W  et al. Low expression of N-myc downstream-regulated gene 2 in oesophageal squamous cell carcinoma correlates with a poor prognosis. BMC Cancer 13:305 (2013). WB, IHC-P, ICC/IF ; Human . Read more (PubMed: 23800335) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"