製品の概要

  • 製品名Anti-NDRG2 antibody
    NDRG2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to NDRG2
  • 特異性ab113439 is expected to recognize reported isoform a (NP_963293.1) only. Reported variants represent identical protein: NP_963831.1, NP_963293.1, NP_963834.1, NP_963833.1.
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
    交差が予測される動物種: Horse, Dog
  • 免疫原

    Synthetic peptide corresponding to Human NDRG2 aa 25-39 (N terminal).
    Sequence:

    KEAELAARILLDQGQ-C


    Database link: Q9UN36

  • ポジティブ・コントロール
    • Human Brain (Temporal Cortex), Mouse and Rat Brain lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.

Antibody detection limit dilution 1:16,000.

WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).

ターゲット情報

  • 機能May be involved in dendritic cell and neuron differentiation. May have anti-tumor activity.
  • 組織特異性Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
  • 配列類似性Belongs to the NDRG family.
  • 発生段階Specifically expressed during dendritic cell differentiation (in vitro). Expression is low in fetal brain and increases during brain postnatal development.
  • 細胞内局在Cytoplasm. Cytoplasm > perinuclear region. Perinuclear in neurons.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Antidepressant related protein ADRG123 antibody
    • Cytoplasmic protein Ndr1 antibody
    • DKFZp781G1938 antibody
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    • KIAA1248 antibody
    • N myc downstream regulated gene 2 antibody
    • N myc downstream regulator 2 antibody
    • NDR1 related protein NDR2 antibody
    • NDRG 2 antibody
    • NDRG family member 2 antibody
    • NDRG1 related protein antibody
    • NDRG2 antibody
    • NDRG2_HUMAN antibody
    • Protein NDRG2 antibody
    • Protein Syld709613 antibody
    • SYLD antibody
    • Syld709613 protein antibody
    see all

Anti-NDRG2 antibody 画像

  • All lanes : Anti-NDRG2 antibody (ab113439) at 0.3 µg/ml

    Lane 1 : Mouse Brain lysate
    Lane 2 : Rat Brain lysate

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 41 kDa
  • Anti-NDRG2 antibody (ab113439) at 0.1 µg/ml + Human Temporal Cortex lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 41 kDa

Anti-NDRG2 antibody (ab113439) 使用論文

ab113439 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"