製品の概要

  • 製品名Anti-NDE1 antibody
    NDE1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to NDE1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-336 of Human NDE1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57430 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Required for centrosome duplication. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex (By similarity). Required for formation and function of the mitotic spindle.
    • 配列類似性Belongs to the nudE family.
    • 翻訳後修飾Phosphorylated in mitosis.
    • 細胞内局在Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle. Cleavage furrow. Localizes to the interphase centrosome and to the mitotic spindle. Concentrates at the plus ends of microtubules coincident with kinetochores in metaphase and anaphase in a CENPF-dependent manner. Also localizes to the cleavage furrow during cytokinesis.
    • Information by UniProt
    • 参照データベース
    • 別名
      • FLJ20101 antibody
      • HOM TES 87 antibody
      • LIS1 interacting protein NUDE1 rat homolog antibody
      • LIS1 interacting protein NUDE1 antibody
      • LIS4 antibody
      • NDE 1 antibody
      • NDE1 antibody
      • NDE1_HUMAN antibody
      • Nuclear distribution gene E homolog 1 antibody
      • Nuclear distribution protein nudE homolog 1 antibody
      • NUDE 1 antibody
      • NudE antibody
      • NudE nuclear distribution gene E homolog 1 (A. nidulans) antibody
      • NudE nuclear distribution gene E homolog 1 antibody
      • NUDE1 antibody
      see all

    Anti-NDE1 antibody 画像



    • Predicted band size : 38 kDa
      NDE1 antibody (ab57430) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-NDE1 antibody (ab57430) 使用論文

    This product has been referenced in:
    • Bradshaw NJ  et al. NDE1 and NDEL1: multimerisation, alternate splicing and DISC1 interaction. Neurosci Lett 449:228-33 (2009). WB . Read more (PubMed: 19000741) »
    • Brophy TM  et al. RN181, a novel ubiquitin E3 ligase that interacts with the KVGFFKR motif of platelet integrin alpha(IIb)beta3. Biochem Biophys Res Commun 369:1088-93 (2008). WB ; Human . Read more (PubMed: 18331836) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab57430.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"