製品の概要

  • 製品名Anti-NDC1 antibody
  • 製品の詳細
    Rabbit polyclonal to NDC1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 323-372 (PPIIKYLALQ DLMLLSQYSP SRRQEVFSLS QPGGHPHNWT AISRECLNLL) of Human NDC1, NP_060557.

  • ポジティブ・コントロール
    • Fetal lung lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab83876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 75, >90 kDa (predicted molecular weight: 75 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性NDC1 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. NDC1 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane. NDC1 colocalizes with p62 (NUP62) on the nuclear envelope at the nuclear rim. The protein has 6 transmembrane domains and several putative phosphorylation sites.
  • 細胞内局在Nucleus; nuclear pore complex; multipass membrane protein
  • 参照データベース
  • 別名
    • FLJ10407 antibody
    • FLJ12556 antibody
    • FLJ34120 antibody
    • hNDC1 antibody
    • TMEM48 antibody
    • Transmembrane protein 48 antibody
    see all

Anti-NDC1 antibody 画像

  • Anti-NDC1 antibody (ab83876) at 1 µg/ml + fetal lung lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 75 kDa
    Observed band size : 75,>90 kDa (why is the actual band size different from the predicted?)

Anti-NDC1 antibody (ab83876) 使用論文

This product has been referenced in:
  • Tarazón E  et al. Heart failure induces significant changes in nuclear pore complex of human cardiomyocytes. PLoS One 7:e48957 (2012). WB ; Human . Read more (PubMed: 23152829) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"