Anti-NCR1 抗体 [MM0491-8F24] (ab89877)
Key features and details
- Mouse monoclonal [MM0491-8F24] to NCR1
- Suitable for: IHC-Fr, Flow Cyt, WB
- Reacts with: Human
- Isotype: IgG2b
製品の概要
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製品名
Anti-NCR1 antibody [MM0491-8F24]
NCR1 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MM0491-8F24] to NCR1 -
由来種
Mouse -
アプリケーション
適用あり: IHC-Fr, Flow Cyt, WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to the extracellular domain of Human NCR1.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and sterile filtered through a 0.2 µm filter. -
ポリ/モノ
モノクローナル -
クローン名
MM0491-8F24 -
アイソタイプ
IgG2b -
研究分野
関連製品
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab89877の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-Fr | (1) |
Use at an assay dependent concentration.
|
Flow Cyt | (2) |
Use at an assay dependent concentration.
ab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
WB | (1) |
Use at an assay dependent concentration.
|
特記事項 |
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IHC-Fr
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. ab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. -
組織特異性
Selectively expressed by both resting and activated NK cells. -
配列類似性
Belongs to the natural cytotoxicity receptor (NCR) family.
Contains 2 Ig-like (immunoglobulin-like) domains. -
翻訳後修飾
N-glycosylated.
O-glycosylated. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 9437 Human
- Omim: 604530 Human
- SwissProt: O76036 Human
- Unigene: 97084 Human
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別名
- Activating NK receptor NK p46 antibody
- CD335 antibody
- FLJ99094 antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (1)
ab89877 は 1 報の論文で使用されています。
- Morita H et al. Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid. J Allergy Clin Immunol 143:2190-2201.e9 (2019). PubMed: 30682454