製品の概要

  • 製品名Anti-NCF1 (phospho S304) antibody
    NCF1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NCF1 (phospho S304)
  • 特異性Detects NCF1 only when phosphorylated at serine 304.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic phosphopeptide derived from human NCF1 around the phosphorylation site of serine 304 (R-S-SP-I-R).

  • ポジティブ・コントロール
    • COS7 cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab63554 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).
ELISA 1/15000.

ターゲット情報

  • 機能NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
  • 関連疾患Defects in NCF1 are the cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 1 (CGD1) [MIM:233700]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
  • 配列類似性Contains 1 PX (phox homology) domain.
    Contains 2 SH3 domains.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 47 kDa autosomal chronic granulomatous disease protein antibody
    • 47 kDa neutrophil oxidase factor antibody
    • NADPH oxidase organizer 2 antibody
    • NCF 47K antibody
    • NCF-1 antibody
    • NCF-47K antibody
    • Ncf1 antibody
    • NCF1_HUMAN antibody
    • Neutrophil cytosol factor 1 antibody
    • Neutrophil cytosolic factor 1 antibody
    • neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) antibody
    • Neutrophil NADPH oxidase factor 1 antibody
    • Nox organizer 2 antibody
    • Nox organizing protein 2 antibody
    • Nox-organizing protein 2 antibody
    • NOXO2 antibody
    • p47 phox antibody
    • p47-phox antibody
    • SH3 and PX domain containing protein 1A antibody
    • SH3 and PX domain-containing protein 1A antibody
    • SH3PXD1A antibody
    see all

Anti-NCF1 (phospho S304) antibody 画像

  • All lanes : Anti-NCF1 (phospho S304) antibody (ab63554) at 1/500 dilution

    Lane 1 : extracts from COS7 cells treated with UV (15mins)
    Lane 2 : A549 cells extracts
    Lane 3 : A549 cells extracts with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 45 kDa
    Observed band size : 45 kDa

Anti-NCF1 (phospho S304) antibody (ab63554) 使用論文

This product has been referenced in:
  • Leverence JT  et al. Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: Role of PKC?-mediated p47phox phosphorylation. Chem Biol Interact : (2010). WB ; Human . Read more (PubMed: 20920494) »

See 1 Publication for this product

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DISCOUNT CODE: XXXXXXX
Expiration date: 31-05-2013
Value: £235

I am very pleased to hear you would like to accept our offer and test ab63554 in Flow Cytometry. This code will give you ab63554 off your next order before the expiration d...

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Yes we have antibodies to detect the p47PHOX. The common alternative namesfor p47phox is NCF1, NOXO2 and SH3PXD1A.http://www.uniprot.org/uniprot/P14598

The antibodies we have are; ab74095, ab63331, ab11...

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Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products. I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"