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Our Abpromise guarantee covers the use of ab63978 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Definition of 1HU is activation of 50% hemolysis by incubating 3% sheep red blood cells at 37? for 30 minutes.
Information about health hazards:
Target: Cholesterol on human and animal cell membrane
Health Hazards: May be fatal if enters bloodstream.
LD50-Lethal dose (50 percent kill) intravenous,
Rabbit, 1500 ng/kg (Ref :PHTHDT Pharmacology and Therapeutics. (Pergamon Press Ltd.,Headington Hill Hall, Oxford OX3 0BW, UK) Vol.(Issue) 11, Page 661,1981 )
Guinea pig, 12 ug/kg (Ref: BICMBE Biochimie. (SPPIF, B.P.22, F-41353 Vineuil, France, Vol.(Issue)55,Page 1187, 1973)
Toxicity is much less when introduced via other routes of entry like interdermal injection.
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 50% Glycerol, PBS, 1mM DTT
This product is an active protein and may elicit a biological response in vivo, handle with caution.
SDS-PAGE analysis of purified Natural Streptolysin O (Hemolytic streptococcus) protein (ab63978).