製品の概要

製品の詳細

  • 由来
    Native
  • 由来
    Native
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Rat
    • 分子量
      54 kDa
    • 領域
      1 to 482

特性

Our Abpromise guarantee covers the use of ab119819 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    Activity is measured in a Factor Xa clotting assay and/or chromogenic substrate assay.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.

  • 製品の状態
    Liquid
  • 備考
    Thaw rapidly in a 37oC water bath without allowing protein to warm to 37oC and immediately cool on ice.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: 0.32% Tris HCl, 4.06% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • Activated factor Xa heavy chain
    • Coagulation factor X
    • F10
    • FA10_HUMAN
    • FX
    • FXA
    • Prothrombinase
    • Stuart factor
    • Stuart Prower factor
    • Stuart-Prower factor
    see all
  • 機能
    Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
  • 組織特異性
    Plasma; synthesized in the liver.
  • 配列類似性
    Belongs to the peptidase S1 family.
    Contains 2 EGF-like domains.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.
    Contains 1 peptidase S1 domain.
  • 翻訳後修飾
    The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
    N- and O-glycosylated.
    The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).
    The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab119819 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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