製品の概要
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製品名Natural mouse NGF protein
NGF タンパク質・ペプチド 製品一覧 -
タンパク質長Full length protein
製品の詳細
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由来Native
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由来Native
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アミノ酸配列
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生物種Mouse
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配列SSTHPVFHMGEF SVCDSVSVWV GDKTTATDIK GKEVTVLAEV NINNSVFRQY FFETKCRASN PVESGCRGID SKHWNSYCTT THTFVKALTT DEKQAAWRFI RIDTACVCVL SRKATRRG
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分子量13 kDa
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領域122 to 241
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配列の追加情報NGF beta Mouse produced in Submaxillary Gland of Grown Mouse is a homodimer, non-glycosylated, polypeptide chain containing 2 identical 120 amino acids.
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab69757 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Functional Studies
SDS-PAGE
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精製度> 95 % SDS-PAGE.
Purity: greater than 98% as determined by: analysis by RP-HPLC and analysis by SDS-PAGE. -
製品の状態Lyophilised
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: None
Constituents: 5% Mannitol and 1% HSAThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Reconstitute in sterile 18MOhms/cm water, to not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
関連情報
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別名
- Beta nerve growth factor
- Beta NGF
- Beta-nerve growth factor
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機能Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
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関連疾患Neuropathy, hereditary sensory and autonomic, 5
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配列類似性Belongs to the NGF-beta family.
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細胞内局在Secreted.
- Information by UniProt
Natural mouse NGF protein (ab69757) 使用論文
ab69757 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"